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Nowadays, following years of technological development, Virtual Observatory standards, resources, and services became powerful enough to help astronomers making real science on everyday basis. The key to the VO success is its entire transparency for a scientific user. This allows an astronomer to combine ``online′′ VO-enabled parts with ``offline′′ research stages including dedicated data processing and analysis, observations, numerical simulations; and helps to overpass one of the major issues that most present-day VO studies do not go further than data mining. Here I will present three VO-science projects combining VO and non-VO blocks, all of them resulted in peer-reviewed publications submitted to major astronomical journals. (1) We have used a VO-fed workflow to automatically analyse a large amount of HST data and discovered a population of compact elliptical (M32-like) galaxies in nearby clusters. Some of these galaxies were later observed with the 6-m telescope to confirm their membership in the clusters, some others were confirmed by analysing archival spectra also available in the VO. We have performed dedicated numerical simulations to model their origin by the tidal stripping, demonstrating the importance of this galaxy evolution mechanism. (2) We have cross-identified three large sources of photometric data: GALEX GR4 (UV), SDSS DR7 (optical), UKIDSS DR5 (NIR) and compiled a homogeneous FUV-to-NIR catalogue of spectral energy distributions of nearby galaxies (0.03<z<0.6). We have extracted the data for the spectroscopically confirmed galaxies and fitted their SDSS DR7 spectra to obtain stellar population parameters, velocity dispersion and residual emission line fluxes of some 190000 galaxies. By using VO tools and technologies, all the computational part of the study was completed in a week after the UKIDSS Data Release 5. (3) The GalMer database is a part of the Horizon project, providing access to a library of TreeSPH simulations of galaxy interactions. We have developed a set of value-added tools related for data visualization and post-processing with available VO-interfaces, including the spectrophotometric modelling of galaxy properties, making GalMer the most advanced resource providing online access to the results of numerical simulations. These tools allow direct comparison of simulations with imaging and spectroscopic observations. Presentation of these three examples aim at stimulating usual astronomers to carry out VO-enabled research on everyday basis. Although minor infrastructural difficulties still exist, VO-enabled research beyond data mining is already possible. We foresee a growing amount of VO-powered studies to arrive in near future.
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